9/18/2023 0 Comments Malate aspartate shuttle![]() To all direct and indirect annotations download (limited to first 10,000)įor malate-aspartate shuttle ( excluding "regulates"). To malate-aspartate shuttle ( excluding "regulates"). to pyruvate is imported into the mitochondria via the malate-aspartate shuttle and regenerated via the ETC to maintain continuous glucose oxidation. These electrons enter the electron transport chain of the mitochondria via reduction. To all genes and gene products annotated to malate-aspartate shuttle ( excluding "regulates"). The malate-aspartate shuttle (sometimes simply the malate shuttle) is a biochemical system for translocating electrons produced during glycolysis across the semipermeable inner membrane of the mitochondrion for oxidative phosphorylation in eukaryotes. GOC:jl Comment None History See term history for GO:0043490 at QuickGO Subset None Related Link ![]() Data health Accession GO:0043490 Name malate-aspartate shuttle Ontology biological_process Synonyms malate aspartate shuttle, malate/aspartate shuttle, malate:aspartate shuttle Alternate IDs None Definition The process of transferring reducing equivalents from the cytosol into the mitochondria NADH is used to synthesise malate in the cytosol this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle. ![]()
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